Graves’ Disease: Causes, Symptoms & Treatments You Need to Know

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Graves' disease, thyroid illustration

Graves’ disease is a complex and often misunderstood condition. It’s an autoimmune disease, which means your body’s immune system mistakenly attacks its own tissues. In this case, it attacks the thyroid gland, causing it to produce too much thyroid hormone. This leads to a condition known as hyperthyroidism. The information in this article is based on genuine human research and is meant for educational purposes to help you better understand this condition.

Understanding the Cause and Symptoms

What is the main cause of Graves’ disease?

The primary cause of Graves’ disease is the overproduction of a specific antibody called thyroid-stimulating immunoglobulin (TSI). This antibody attaches to the thyroid gland and makes it produce an excessive amount of thyroid hormones. While genetics is a significant risk factor, environmental triggers like high stress, pregnancy, and viral infections may also play a role.

Infographic showing Graves’ disease symptoms, rapid heartbeat, heat intolerance, anxiety, Graves’ disease

What are three symptoms of Graves’ disease?

Symptoms can appear gradually or suddenly. Three of the most common are:

  1. Rapid Heartbeat: You may feel your heart racing, a condition known as tachycardia.
  2. Heat Intolerance: People with this condition often feel hot all the time and sweat excessively.
  3. Nervousness or Anxiety: An overactive thyroid can speed up your body’s functions, leading to feelings of anxiety and shakiness.

What does Graves’ disease do to your appearance?
Graves’ disease can cause physical changes that are visible. About one-third of people with the condition develop eye issues known as Graves’ orbitopathy. This can cause bulging eyes, double vision, and light sensitivity. In some cases, it may also cause a lumpy, discolored thickening of the skin, typically on the legs.

Medical illustration of Graves’ orbitopathy with bulging eyes and thickened leg skin, Graves' Disease

What are the worst symptoms of Graves’ disease?
While many symptoms can be uncomfortable, a rare but life-threatening complication is a thyroid storm. This happens when the thyroid gland releases a large amount of hormones in a short period. It can lead to an extremely high fever and a very fast heart rate, and can even cause heart failure. A thyroid storm requires immediate emergency medical attention.

Diagnosis and Treatment

How to test for Graves’ disease?
To diagnose Graves’ disease, a doctor will perform a physical exam and review your symptoms and family history. They will likely recommend blood tests to check your thyroid hormone levels and look for specific antibodies. A thyroid uptake and scan, which uses a small amount of radioactive iodine, may also be used to see how your thyroid is functioning. In some cases, a Doppler ultrasound might be used, especially if the iodine scan is not an option.

Doctor discussing thyroid scan results with patient in clinical setting, Graves' disease

What is the best treatment for Graves’ disease?
There is no single “best” treatment. The right choice depends on your age, health, and the severity of your condition. Treatments can help control hormone levels and may even lead to remission. Options include:

  1. Medications: Beta-blockers can help manage symptoms like a rapid heart rate, while antithyroid medications can block hormone production.
  2. Radioiodine Therapy: This treatment slowly destroys the thyroid cells, causing the gland to shrink and hormone levels to return to normal.
  3. Surgery: A thyroidectomy, which involves removing all or part of the thyroid, is another option.

Living with Graves’ Disease

What not to do with Graves’ disease?
It is crucial not to ignore your symptoms. Graves’ disease is not a condition you should try to manage on your own. It’s essential to get a professional medical diagnosis and follow your doctor’s treatment plan. Untreated, the condition can lead to severe health complications.

What is the life expectancy of people with Graves’ disease?
With proper medical care, a person with Graves’ disease can live a normal, healthy life. The condition is very manageable. However, if left untreated, it can increase your risk of serious long-term problems like heart disease and osteoporosis.

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